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. 2021 May 13;8:639361. doi: 10.3389/fcvm.2021.639361

Table 3.

Participant characteristics of monocyte transcriptome analysis.

Demographics Without SVD progression Incident lesions
Age, years 71 ± 2 79 ± 9
Sex, % men 1 (25) 3 (75)
BMI, kg/m2 27.0 ± 4.2 28.2 ± 4.4
Hypertension 4 (100) 4 (100)
Smoking, % active 1 (25) 0 (0)
Baseline WMH volume, ml 6.23 (1.41–10.54) 10.15 (6.28–23.27)
Baseline WMH, % of WM 1.54 (0.34–3.46) 2.69 (1.65–5.96)
WMH progression, ml/month 0.01 (0.00–0.05) 0.08 (0.00–0.20)

Participants with incident DWI+ lesions (n = 4) were matched to subjects without SVD progression (n = 4) for RNA sequencing. Mean ± SD, mean (number), and median (IQR). BMI, body mass index; DWI+, diffusion-weighted imaging-positive; IQR, interquartile range; SVD, small vessel disease; WMH, white matter hyperintensity. The bold values are statistically significant.