Table 3.
Demographics | Without SVD progression | Incident lesions |
---|---|---|
Age, years | 71 ± 2 | 79 ± 9 |
Sex, % men | 1 (25) | 3 (75) |
BMI, kg/m2 | 27.0 ± 4.2 | 28.2 ± 4.4 |
Hypertension | 4 (100) | 4 (100) |
Smoking, % active | 1 (25) | 0 (0) |
Baseline WMH volume, ml | 6.23 (1.41–10.54) | 10.15 (6.28–23.27) |
Baseline WMH, % of WM | 1.54 (0.34–3.46) | 2.69 (1.65–5.96) |
WMH progression, ml/month | 0.01 (0.00–0.05) | 0.08 (0.00–0.20) |
Participants with incident DWI+ lesions (n = 4) were matched to subjects without SVD progression (n = 4) for RNA sequencing. Mean ± SD, mean (number), and median (IQR). BMI, body mass index; DWI+, diffusion-weighted imaging-positive; IQR, interquartile range; SVD, small vessel disease; WMH, white matter hyperintensity. The bold values are statistically significant.