Table 4.
Correlation analyses between the MRI results and cognitive z-scores.
| EF | A/WM | EM | VF | LAN | |
|---|---|---|---|---|---|
| Shape analysis | |||||
| Left caudate nucleus | rS = 0.14; pFDR = 0.690 | rS = 0.009; pFDR = 1.000 | rS = 0.001; pFDR = 0.990 | rS = −0.03; pFDR = 1.000 | rS = 0.1; pFDR = 0.760 |
| Right caudate nucleus | rS = 0.19; pFDR = 0.245 | rS = 0.04; pFDR = 1.000 | rS = 0.01; pFDR = 0.919 | rS = −0.01; pFDR = 1.000 | rS = 0.08; pFDR = 1.000 |
| Right thalamus | rS = 0.13; pFDR = 0.302 | rS = 0.19; pFDR = 0.260 | rS = 0.01; pFDR = 0.885 | rS = 0.06; pFDR = 0.630 | rS = 0.16; pFDR = 0.260 |
| Right hippocampus | rS = 0.27; pFDR = 0.025* | rS = 0.26; pFDR = 0.015* | rS = 0.24; pFDR = 0.019* | rS = 0.16; pFDR = 0.106 | rS = 0.18; pFDR = 0.072 |
| Texture | |||||
| Kurtosis—Right hippocampus | rS = 0.24; pFDR = 0.034* | rS = 0.13; pFDR = 0.196 | rS = 0.08; pFDR = 0.545 | rS = 0.34; pFDR = 0.002* | rS = 0.02; pFDR = 0.824 |
| Tractometry | |||||
| FA—Right superior longitudinal fascicle (part III) | rS = 0.12; pFDR = 0.375 | rS = 0.19; pFDR = 0.255 | rS = 0.04; pFDR = 0.878 | rS = 0.13; pFDR = 0.453 | rS = −0.03; pFDR = 0.764 |
| FA—Right inferior fronto-occipital fascicle | rS = 0.17; pFDR = 0.530 | rS = 0.16; pFDR = 0.30 | rS = −0.01; pFDR = 0.914 | rS = 0.07; pFDR = 0.592 | rS = 0.10; pFDR = 0.584 |
| FA—Left striato-parietal tract | rS = 0.12; pFDR = 0.379 | rS = 0.15; pFDR = 0.360 | rS = 0.09; pFDR = 0.492 | rS = 0.19; pFDR = 0.260 | rS = −0.02; pFDR = 0.824 |
| FA—Tract connecting the isthmus to parieto-temporal cortex | rS = 0.08; pFDR = 1.000 | rS = 0.08; pFDR = 0.719 | rS = 0.004; pFDR = 0.971 | rS = 0.08; pFDR = 0.544 | rS = 0.15; pFDR = 0.600 |
| FA—Tract connecting the genu to frontal cortex | rS = 0.09; pFDR = 0.975 | rS = 0.19; pFDR = 0.305 | rS = 0.002; pFDR = 0.981 | rS = 0.03; pFDR = 0.914 | rS = 0.04; pFDR = 1.000 |
| MD—Tract connecting the posterior midbody of the corpus callosum to postcentral cortex | rS = −0.11; pFDR = 0.658 | rS = −0.06; pFDR = 0.650 | rS = 0.02; pFDR = 0.838 | rS = −0.26; pFDR = 0.045* | rS = −0.11; pFDR = 0.484 |
Results are considered significant at *pFDR < 0.05 (corrected for age, sex, years of formal education, and center). FA, fractional anisotropy; MD, mean diffusivity; A/WM, attention/working memory; EF, executive functions; VF, visuospatial functions; EM, episodic memory; LAN, language; FDR, false discovery rate.