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. 2021 Apr 19;7(1):veab038. doi: 10.1093/ve/veab038

Table 2.

Nucleotide-level statistics of mutations.

Strand N M Nn Nv r α (n1,n2,n3) (z1:z2:z3)
CxNV1-RdRp 1033 46 606 362 0.0068 3.35 (181, 140, 645) (0.56:0.44:2.00)
ZJMV3-RdRp 1075 12 210 39 0.0064 10.80 (47, 29, 173) (0.57:0.35:2.08)
CxNV1-Robin 272 46 213 146 0.0096 2.92 (107, 100, 152) (0.89:0.84:1.27)
ZJMV3-Robin 304 10 84 48 0.0145 3.50 (35, 31, 66) (0.80:0.70:1.50)

The consensus sequence has N codons. Among the mutations observed in M polymorphs, there are Nn transitions, Nv transversions, with overall rate r and transition/transversion rate ratio α. The numbers total mutations at each base position is (n1:n2:n3), and normalising these to ratios via Equation (6) yields (z1:z2:z3).