Table 4.

Summary of results of the mutational hotspots test.

Sample	$\langle n(k)\rangle$	$\langle f(k)\rangle$	Gene	N	$N_{\text{ds}}$	Rn	Rf
Double syns., CxNV1-RdRp	0.954	0.161	CxNV1-RdRp	1033	220	0.986	1.044
Other codons, CxNV1-RdRp	0.968	0.155	ZJMV3-RdRp	1075	219	0.975	0.840
Double syns., ZJMV3-RdRp	1.20	0.042	CxNV1-Robin	272	54	1.19	1.16
Other codons, ZJMV3-RdRp	1.23	0.050	ZJMV3-Robin	304	81	0.926	0.978
Double syns, CxNV1-Robin	1.76	0.195
Other codons, CxNV1Robin	1.48	0.169
Double syns, ZJMV3-Robin	0.889	0.096
Other codons, ZJMV3-Robin	0.960	0.097

Left panel: values of the average number of elements of the variant set, $\langle n(k)\rangle$ and of the average fraction of non-consensus codons, $\langle f(k)\rangle$, for double-synonym sites, and for the other sites. Right panel: N is the number of loci in the alignment, $N_{\text{ds}}$ is the number of double-synonym loci, and R_n, R_f are the ratios of $\langle n(k)\rangle$ and $\langle f(k)\rangle$ at double-synonym sites to their values at other sites. The differences of these ratios from unity do not appear significant.