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. 2021 May 13;12:670054. doi: 10.3389/fphar.2021.670054

FIGURE 2.

FIGURE 2

SGD alleviated the chronic low-grade inflammation in PCOS rats. (A–D) Serum levels of inflammatory cytokines including TNF-α, IL-1β, IL-6, and IL-18 were determined by using ELISA kits (n = 10). (E–H) The mRNA levels of inflammatory cytokines including TNF-α, IL-1β, IL-6, and IL-18 in rats ovarian tissues were quantitated by real-time PCR (n = 5). Data were presented as mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. normal group, ## p < 0.01 and ### p < 0.001 vs. PCOS model group.