Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
c-MET involvement with pediatric NS tumors. Various reports have demonstrated the involvement of c-MET/HGF signaling in pediatric nervous system tumors leading to enhanced malignancy and metastatic potential, therapeutic evasion, and poor survival. Abbreviations: c-MET, mesenchymal epithelial transition factor; HGF, hepatocyte growth factor; DIPG, diffuse intrinsic pontine glioma; SHH, Sonic Hedgehog; STAT3, signal transducer and activator of transcription 3.
