Skip to main content
. 2021 May 13;9:654103. doi: 10.3389/fcell.2021.654103

Figure 3.

Figure 3

Protein-protein interactions between MET and tumorigenic markers in brain CSCs. String functional association networks reveal known interactions between MET and other tumorigenic players identified in brain CSCs. Known interactions were identified experimentally (pink lines), from curated databases (blue lines), and predicted interactions were identified as co-expressed proteins (black lines) and from text mining (green lines). Abbreviations: EZH2, enhancer of zeste homolog 2; SOX2, sex-determining region Y-box 2; PDGFRA, platelet-derived growth factor receptor A; GLI 1, glioma-associated oncogene homolog 1; FOXG 1, forkhead box protein G1; STAT 3, signal transducer and activator of transcription 3; BMI 1, B lymphoma Mo-MLV insertion region 1 homolog; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; NANOG, transcription factor that is involved in the self-renewal of embryonic stem cells; LAMC 1, laminin subunit gamma-1 precursor; AKT 1, AK strain transforming 1; MYC, proto-oncogene, bHLH transcription factor; MYCN, v-myc myelocytomatosis viral-related oncogene, neuroblastoma-derived; FOXM 1, forkhead box M1; LAMB 1, laminin subunit beta-1; TNF, tumor necrosis factor.