TABLE 2.

Key to murine model clinical outcomes.

Score	Histologic findings	Clinical scores	Gross lung pathology
0	Within normal limits	Healthy appearance and activity	Within normal limits
1	Presence of inflammatory cells	Scruffy appearance	Darker red
2	Presence of interstitial inflammation and fibrotic foci	Scruffy and dehydrated	Few nodules
3	Interstitial and alveolar inflammation, fibrosis	Scruffy, dehydrated and decreased activity	Several nodules, <25% consolidation
4	N/A	Scruffy, dehydrated and minimal activity	Numerous nodules 25–50% consolidation
5	N/A	Moribund or dead	Numerous nodules>50% consolidation