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. 2021 May 13;12:651750. doi: 10.3389/fneur.2021.651750

Table 3.

Main biochemical parameters.

Variables EM (n = 32) CM-MOH (n = 34) TTH (n = 10) Chi-square; p F; p
Variable (abnormal range) OOR Mean ± SD OOR Mean ± SD OOR Mean ± SD
VitD, ng/ml (<20) 28.1% 19.9 ± 11.4 64.7% 20.1 ± 5.9 40% 23.8 ± 17.5 χ2 = 9.05; p = 0.011 F = 0.6; p = 0.57
Ca, mg/dl (<8.6–>10.2) 3.1% 9.9 ± 0.6 5.9% 9 ± 1.9 0% 9.4 ± 0.2 χ2 = 0.80; p = 0.7 F = 0.31; p = 0.74
P, mg/dl (<2.5) 3.1% 3.4 ± 0.4 0% 3.3 ± 0.3 0% 3.4 ± 0.3 χ2 = 1.39; p = 0.5 F = 0.3; p = 0.74
PTH, pg/ml (<15–>88) 8% 33.4 ± 19.6 10.7% 32.5 ± 25.1 0% 37 ± 27.7 χ2 = 0.64; p = 089 F = 0.08; p = 0.92
Folate, ng/ml (<8.1) 21.4% 15 ± 10.8 33.3% 12.1 ± 5.3 26.8% 17.7 ± 16.2 χ2 = 2.06; p = 0.7 F = 1.14; p = 0.33
Vit B12, pg/ml (<133) 20.7% 270.1 ± 145.3 6.9% 315.5 ± 141.8 0.0% 385 ± 144.7 χ2 = 3.84; p = 0.15 F = 2.17; p = 0.12
Homocysteine, μmol/L (>12) 25% 12.8 ± 9.4 47.4% 12.1 ± 3.7 71.4% 14.8 ± 5.8 χ2 = 5.1; p = 0.08 F = 0.31; p = 0.73
Fe, μmol/dl (<33) 15.4% 97.9 ± 43.3 19.2% 76.2 ± 41.8 0.0% 97.7 ± 22.3 χ2 = 1.38; p = 0.5 F = 1.98; p = 0.15

EM, episodic migraine; CM-MOH, chronic migraine and medication overuse headache; TTH, tension-type headache; Ca, calcium; Fe, iron; OOR, out of range; P, phosphate; VitB12, Vitamin B12; vitD, Vitamin D; OOR, out of range. The statistically significant values are reported in bold.