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. 2021 May-Jun;37(3):733–739. doi: 10.12669/pjms.37.3.3670

Table-III.

Association analysis of genotype distribution of 374T/A polymorphism among DNR and NPDR sub-groups.

Genotypes DNR n=150 (%) NPDR Mild n=44 (%) NPDR Moderate n=34 (%) NPDR severe n=22 (%) OR (95% CI) p-value Regression analysis OR (95% C1) p-value
TT 120 (80.0) 39(88.6) 21(61.8) 12(54.5) Ref
TA 26 (17.3) 3(6.8) 12(35.3) 8(36.4) 0.35(0.10-1.23)a
2.63(1.15-6.02)b
3.07(1.14-8.28)c
0.09a
0.01b
0.03c
2.63(1.15 - 6.02)b
3.77(1.42-10.03)c
0.021b
0.008c
AA 4(2.7) 2(4.5) 1(2.9) 2(9.1) 1.53(0.27-8.72)a
1.42(0.15-13.41)b
5(0.82-30.19)c
0.638a
1b
0.113c

“DNR: diabetic with no retinopathy, NPDR: non - proliferative diabetic retinopathy, PDR: proliferative diabetic retinopathy, a: DNR vs NPDR Mild, b: DNR vs NPDR moderate, c: DNR vs NPDR severe.”