Table 1.
Patient demographics and MRI morphological characteristics in the study set.
| Parameter | All Gliomas | IDH Mutation | IDH Wild-Type | P value |
|---|---|---|---|---|
| Number of Patients | 176 | 89 | 87 | |
| Age | 46.5 [35.0,54.0] | 41.0 [33.0,49.0] | 50.0 [40.0,59.0] | <0.001 |
| Sex | ||||
| Female | 67 (38.1) | 31 (34.8) | 36 (41.4) | 0.460 |
| Male | 109 (61.9) | 58 (65.2) | 51 (58.6) | |
| Tumor Location | ||||
| Frontal lobe | 89 (50.6) | 56 (62.9) | 33 (37.9) | 0.010 |
| Other lobes | 74 (42.0) | 29 (32.6) | 45 (51.7) | |
| Thalamus or brainstem | 9 (5.1) | 3 (3.4) | 6 (6.9) | |
| Cerebellum | 4 (2.3) | 1 (1.1) | 3 (3.4) | |
| Diameter | ||||
| <6 cm | 132 (75.0) | 62 (69.7) | 70 (80.5) | 0.139 |
| ≥6 cm | 44 (25.0) | 27 (30.3) | 17 (19.5) | |
| Enhancement | ||||
| Nonenhancement | 63 (35.8) | 53 (59.6) | 10 (11.5) | <0.001 |
| Patchy enhancement | 42 (23.9) | 25 (28.1) | 17 (19.5) | |
| Ring enhancement | 71 (40.3) | 11 (12.4) | 60 (69.0) | |
| Calcification | ||||
| No | 152 (86.4) | 68 (76.4) | 84 (96.6) | <0.001 |
| Yes | 24 (13.6) | 21 (23.6) | 3 (3.4) | |
| Cystic Change | ||||
| No | 73 (41.5) | 48 (53.9) | 25 (28.7) | 0.001 |
| Yes | 103 (58.5) | 41 (46.1) | 62 (71.3) | |
| Hemorrhage | ||||
| No | 91 (51.7) | 63 (70.8) | 28 (32.2) | <0.001 |
| Yes | 85 (48.3) | 26 (29.2) | 59 (67.8) | |
| T2 FLAIR Mismatch | ||||
| No | 136 (77.3) | 62 (69.7) | 74 (85.1) | 0.024 |
| Yes | 40 (22.7) | 27 (30.3) | 13 (14.9) | |
| WHO 2016 Grade | ||||
| Lower-grade Glioma | 102 (58.0) | 78 (88.7) | 23 (26.4) | <0.001 |
| Glioblastoma | 74 (42.0) | 10 (11.2) | 64 (73.6) |
Data in parentheses are ranges, and data in brackets are interquartile ranges.
IDH, isocitrate dehydrogenase; FLAIR, fluid-attenuated inversion recovery.