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. 2021 May 13;9:671841. doi: 10.3389/fcell.2021.671841

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Copyright © 2021 Chu, Taghizadeh, Vazquez-Armendariz, Herold, Chong, Chen, Zhang, El Agha and Bellusci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fgf10^Ki-v2/+; tdTom^flox/+ adult lungs display enhanced number of tdTom^Pos cells compared with to the Fgf10^Ki-v1/+; tdTom^flox/+ adult lungs. (A) 2-months-old; Fgf10^Ki-v1/+; tdTom^flox/+ and Fgf10^Ki-v2/+; tdTom^flox/+ mice received 3 Tam IPs or oil at P61, P63 and P65 and were sacrificed at P67. (B) Whole-mount fluorescence images of oil-treated Fgf10^Ki-v2/+; tdTom^flox/+, Tam-treated Fgf10^Ki-v2/+; tdTom^flox/+ and Tam-treated Fgf10^Ki-v1/+; tdTom^flox/+ lungs at P67. Higher magnification of the lungs are shown in the lower panel. (C) Flow cytometry analysis of Fgf10^Ki-v2/+; tdTom^flox/flox lung homogenate. Scale bar in (B): low magnification: 2.5 mm, High magnification: 0.75 mm.