Table 2.
Summary statistics for analysis of subcortical regional volumes, showing: (1) the main effects of group, i.e., the chronic cannabis use group (CAN) vs. controls (CTL); (2) the main effect of sex, i.e., Males (M) vs. Females (F); and (3) their interaction.
| Region | Group: CAN > CTL t (padj) | Sex: M > F t (padj) | Interaction: t (padj) |
|---|---|---|---|
| Cerebellar cortex | −3.353 (0.009) | 1.82 (0.232) | 3.699 (0.003) |
| Cerebellar WM | −0.835 (0.763) | 1.126 (0.473) | 1.323 (0.374) |
| Amygdala | −2.611 (0.047) | 1.884 (0.232) | 1.78 (0.374) |
| Hippocampus | −1.341 (0.603) | 1.228 (0.473) | 1.434 (0.374) |
| Putamen | 0.623 (0.763) | 1.85 (0.232) | −0.1 (0.921) |
| Caudate | −0.422 (0.842) | −0.974 (0.473) | 0.413 (0.756) |
| Accumbens | −1.101 (0.679) | 1.059 (0.473) | 1.446 (0.374) |
| Thalamus | −0.266 (0.871) | 0.379 (0.881) | 0.681 (0.633) |
| Pallidum | 0.731 (0.763) | −0.07 (0.998) | 0.665 (0.633) |
| Brainstem | 0.162 (0.871) | −0.003 (0.998) | 0.911 (0.605) |
All p-values are adjusted using False Discovery Rate Benjamini-Hochberg Correction. WM, White Matter. Bold values denote statistical significance (p < 0.05).