Table 1.
Comparisons of baseline characteristics between short- and long-term survivors.
| Variables | All (n=211) | STS (n=167) | LTS (n=44) | P value |
|---|---|---|---|---|
| Age at diagnosis (years) | 49.0 ± 11.8 | 49.9 ± 11.3 | 41.2 ± 11.1 | <0.001 |
| Gender | 0.432 | |||
| Male | 126/211 | 102/167 | 24/44 | |
| KPS score | 80.0 ± 14.2 | 76.2 ± 14.9 | 82.2 ± 8.3 | 0.002 |
| Tumor size (mm) | 49.2 ± 18.9 | 49.5 ± 19.1 | 48.1 ± 18.3 | 0.652 |
| Tumor location | 0.039* | |||
| Frontal | 86/211 | 60/167 | 26/44 | |
| Temporal | 56/211 | 45/167 | 11/44 | |
| Parietal | 35/211 | 32/167 | 3/44 | |
| Occipital | 18/211 | 16/167 | 2/44 | |
| Others | 16/211 | 14/167 | 2/44 | |
| Laterality | 0.138 | |||
| Right | 92/211 | 67/167 | 25/44 | |
| Left | 95/211 | 80/167 | 15/44 | |
| Bilateral | 24/211 | 20/167 | 4/44 | |
| Enhancement | 0.139 | |||
| Solid | 144/211 | 118/167 | 26/44 | |
| Ring | 38/211 | 30/167 | 8/44 | |
| Irregular | 29/211 | 19/167 | 10/44 | |
| Cystic change | <0.001 | |||
| Yes | 57/211 | 32/167 | 25/44 | |
| Extent of resection | <0.001 | |||
| GTR | 91/211 | 53/167 | 38/44 | |
| Chemotherapy | 0.084 | |||
| Temozolomide | 170/211 | 134/167 | 36/44 | |
| Nimostine | 27/211 | 19/167 | 8/44 | |
| None | 14/211 | 14/167 | 0/44 | |
| Radiotherapy | 0.005* | |||
| Yes | 188/211 | 144/167 | 44/44 | |
| Recurrence pattern | 0.838 | |||
| Local | 156/195 | 134/167 | 22/28 | |
| MGMT promotor | <0.001 | |||
| Methylation | 68/160 | 44/126 | 24/34 | |
| IDH | <0.001 | |||
| Mutation | 55/211 | 28/167 | 27/44 | |
| 1q/19p co-polysomy | 0.047 | |||
| Yes | 30/202 | 21/167 | 9/35 | |
| Ki-67 index | 0.510 | |||
| High | 70/193 | 59/158 | 11/35 |
KPS, Karnofsky performance scale; GTR, gross-total resection; MGMT, O6-methylguanine-DNA-methyltransferase; IDH, isocitrate dehydrogenase.
*by Fisher exact test.