Table 2.
Baseline characteristics of the study population.
| Antiplatelet (mono or dual) | Anticoagulation | Antiplatelet and anticoagulation | ||||||
|---|---|---|---|---|---|---|---|---|
| Characteristic | Overall, N = 830 | Antithrombotic naive, N = 360a | N = 267a | p-valueb,c | N = 172a | p-valueb,c | N = 31a | p-valueb,c |
| Age at injury (years) | 76 (71, 83) | 73 (69, 79) | 77 (71, 85) | <0.001 | 81 (74, 86) | <0.001 | 75 (72, 81) | 0.10 |
| Sex | 0.2 | 0.13 | 0.008 | |||||
| Female | 345 (42%) | 165 (46%) | 108 (40%) | 66 (38%) | 6 (19%) | |||
| Male | 485 (58%) | 195 (54%) | 159 (60%) | 106 (62%) | 25 (81%) | |||
| ASAdscore | <0.001 | <0.001 | <0.001 | |||||
| 1. Healthy | 103 (12%) | 100 (28%) | 3 (1.1%) | 0 (0%) | 0 (0%) | |||
| 2. Moderate disease | 304 (37%) | 158 (44%) | 95 (36%) | 45 (26%) | 6 (19%) | |||
| 3. Severe disease | 398 (48%) | 93 (26%) | 160 (60%) | 122 (71%) | 23 (74%) | |||
| 4. Life-threatening disease | 23 (2.8%) | 7 (2.0%) | 9 (3.4%) | 5 (2.9%) | 2 (6.5%) | |||
| Living | <0.001 | 0.002 | 0.070 | |||||
| Home – independent | 622 (76%) | 293 (83%) | 187 (70%) | 120 (71%) | 22 (71%) | |||
| Home - with assistance | 147 (18%) | 44 (12%) | 51 (19%) | 43 (25%) | 9 (29%) | |||
| Institutionalized | 51 (6.2%) | 16 (4.5%) | 28 (11%) | 7 (4.1%) | 0 (0%) | |||
| Other | 2 (0.2%) | 2 (0.6%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| High energy trauma | 0.029 | 0.003 | 0.039 | |||||
| No | 653 (80%) | 261 (75%) | 217 (83%) | 147 (86%) | 28 (93%) | |||
| Yes | 159 (20%) | 88 (25%) | 46 (17%) | 23 (14%) | 2 (6.7%) | |||
| Rotterdam CT score | 0.12 | <0.001 | 0.11 | |||||
| 226 (27%) | 107 (30%) | 71 (27%) | 40 (23%) | 8 (26%) | ||||
| 3 | 431 (52%) | 195 (54%) | 149 (56%) | 72 (42%) | 15 (48%) | |||
| 4 | 89 (11%) | 23 (6.4%) | 29 (11%) | 31 (18%) | 6 (19%) | |||
| 5/6 | 84 (10%) | 35 (9.7%) | 18 (6.7%) | 29 (17%) | 2 (6.5%) | |||
| HISSe | 0.091 | 0.10 | 0.3 | |||||
| Minimal/mild | 404 (49%) | 173 (48%) | 143 (54%) | 74 (43%) | 14 (45%) | |||
| Moderate | 247 (30%) | 106 (30%) | 83 (31%) | 45 (26%) | 13 (42%) | |||
| Severe | 178 (21%) | 80 (22%) | 41 (15%) | 53 (31%) | 4 (13%) | |||
| Multitrauma | 0.047 | 0.077 | 0.011 | |||||
| No | 504 (61%) | 199 (55%) | 170 (64%) | 110 (64%) | 25 (81%) | |||
| Yes | 325 (39%) | 160 (45%) | 97 (36%) | 62 (36%) | 6 (19%) | |||
Two patients had incomplete information on antithrombotics, thus the table gives information on 830 patients.
a
Statistics presented: median (IQR); n (%).
b
Statistical tests performed: Wilcoxon rank-sum test; chi-square test of independence; Fisher's exact test.
c
P-value calculated against Antithrombotic naive group.
d
ASA score: The American Society of Anaestesiologists score.
e
HISS, head injury severity scale.