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. 2021 May 13;12:682415. doi: 10.3389/fimmu.2021.682415

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Copyright © 2021 Zhao, Ou and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional enrichment for gene set associated with high/low expression of NRG3 in patients with LGG. Differentially expressed genes for high expression of NRG3 vs low expression of NRG3 in LGG were shown in the volcano plot (A), with blue dots representing significantly down-regulated genes and orange dots representing significantly up-regulated genes in high expression of NRG3 in LGG, and heatmap exhibits the expression level. Enrichment analysis for KEGG pathway and GO term of down-regulated genes and up-regulated genes in high expression of NRG3 in LGG (B).