TABLE 3.
Statistical analyses of individual gene effects following UCA1 knock-down ± FSK treatment (significant values are in red fonts).
| Overall tests of univariate models | Tests of univariate effects | ||||
| Y variable | F | Prob. | Source | F | Prob. |
| UCA1 | 22.504 | 0.00029659 | Si treatment | 56.948 | 6.6307 × 10–05 |
| Fusion | 4.288 | 0.07213567 | |||
| Si treatment*Fusion | 6.275 | 0.03665572 | |||
| CGB | 8.208 | 0.00797657 | Si treatment | 10.373 | 0.01222583 |
| Fusion | 0.283 | 0.60936093 | |||
| Si treatment*Fusion | 13.967 | 0.00572781 | |||
| CGA | 127.930 | 4.243 × 10–07 | Si treatment | 43.849 | 0.00016558 |
| Fusion | 336.346 | 8.0411 × 10–08 | |||
| Si treatment*Fusion | 3.596 | 0.09452054 | |||
| GCLM | 2.521 | 0.13152052 | Si treatment | 4.143 | 0.07620217 |
| Fusion | 0.975 | 0.3524659 | |||
| Si treatment*Fusion | 2.445 | 0.15650114 | |||
| NOS3 | 14.589 | 0.00131394 | Si treatment | 15.149 | 0.0045949 |
| Fusion | 28.613 | 0.0006866 | |||
| Si treatment*Fusion | 0.004 | 0.95003544 | |||
| CAV1 | 5.155 | 0.02833346 | Si treatment | 7.939 | 0.02257829 |
| Fusion | 7.147 | 0.02821257 | |||
| Si treatment*Fusion | 0.379 | 0.55505375 | |||
| KI67 | 13.163 | 0.00184323 | Si treatment | 34.327 | 0.00037894 |
| Fusion | 0.891 | 0.37283458 | |||
| Si treatment*Fusion | 4.272 | 0.07257943 | |||
| SYN2 | 23.107 | 0.00027009 | Si treatment | 39.848 | 0.00022968 |
| Fusion | 18.244 | 0.00271954 | |||
| Si treatment*Fusion | 11.229 | 0.01006638 | |||
| TGM2 | 51.718 | 1.3944 × 10–05 | Si treatment | 63.473 | 4.4987 × 10–05 |
| Fusion | 84.869 | 1.5606 × 10–05 | |||
| Si treatment*Fusion | 6.811 | 0.0311362 | |||
| ANXA2 | 39.218 | 3.939 × 10–05 | Si treatment | 23.397 | 0.00129298 |
| Fusion | 43.573 | 0.00016922 | |||
| Si treatment*Fusion | 50.685 | 0.00010006 | |||
| ITIH5 | 56.208 | 1.0168 × 10–05 | Si treatment | 37.157 | 0.00029085 |
| Fusion | 125.667 | 3.5958 × 10–06 | |||
| Si treatment*Fusion | 5.801 | 0.04260521 | |||
| SYN1 | 10.209 | 0.00413556 | Si treatment | 15.939 | 0.00399228 |
| Fusion | 14.682 | 0.00500579 | |||
| Si treatment*Fusion | 0.005 | 0.94569912 | |||
| ANXA1 | 96.898 | 1.2527 × 10–06 | Si treatment | 45.870 | 0.00014171 |
| Fusion | 243.711 | 2.8262 × 10–07 | |||
| Si treatment*Fusion | 1.114 | 0.32213654 | |||
| MMP9 | 5.171 | 0.02810927 | Si treatment | 1.134 | 0.31791426 |
| Fusion | 13.560 | 0.00619729 | |||
| Si treatment*Fusion | 0.819 | 0.39182403 | |||
| INHA | 137.727 | 3.1788 × 10–07 | Si treatment | 40.502 | 0.00021729 |
| Fusion | 372.037 | 5.4151 × 10–08 | |||
| Si treatment*Fusion | 0.641 | 0.44650823 | |||
| BAX | 21.540 | 0.00034606 | Si treatment | 36.796 | 0.00030055 |
| Fusion | 25.245 | 0.00102124 | |||
| Si treatment*Fusion | 2.580 | 0.14686479 | |||
| BCL2 | 8.774 | 0.00654947 | Si treatment | 13.427 | 0.00636233 |
| Fusion | 12.786 | 0.00723255 | |||
| Si treatment*Fusion | 0.110 | 0.74867557 | |||
| DAPK1 | 2.339 | 0.14975061 | Si treatment | 2.106 | 0.18480454 |
| Fusion | 2.027 | 0.1923598 | |||
| Si treatment*Fusion | 2.884 | 0.12788132 | |||
| BAD | 32.681 | 7.7268 × 10–05 | Si treatment | 55.723 | 7.1629 × 10–05 |
| Fusion | 36.270 | 0.0003154 | |||
| Si treatment*Fusion | 6.050 | 0.03934242 | |||