Table 4.
Tumor response at 7 days, 1 month and 3 months post FLASH-RT, estimated based on the veterinary RECIST 1.0 criteria for patients with solid tumors, and disease-free interval for patients with microscopic disease.
| Patient no. | 7 days | 1 month | 3 months |
|---|---|---|---|
| 1 | NR | NR | NR |
| 2 | NR | NR | NR |
| 3 | NR | NR | NR |
| 4 | SD | SD | PR |
| SD | SD | SD | |
| 5 | SD† | PD | n/a |
| SD† | PD | n/a | |
| 6 | SD | PR | PR |
| 7 | SD | PR | CR |
| SD | PR | CR | |
| 8 | PR | PR | PR |
| 9 | PR | PD | PD |
| 10 | SD†† | PR/CR†† | CR†† |
R, Recurrence; NR, No recurrence; SD, Stable disease; PR, Partial response; CR, Complete response; PD, Progressive disease; n/a, Not applicable.
†The patient showed PR at 14 days followed by PD at 4 weeks after both the first and second treatment. At 4 weeks after the second treatment the tumor was surgically resected.
††The tumor response for patient no. 10 was based on clinical response and evaluation of nasal airflow.