Table 1.
All group (n = 148) | EOD(n = 91) | LOD (n = 57) | Group comparison, P | |
---|---|---|---|---|
Age at recruitment, mean (sd) | 70.27 (±8.28) | 64.90 (±4.82) | 78.56 (±5.02) | p < 0.001 |
Disease duration (years), mean (sd) | 5.6 (±3.33) | 5.52 (±3.25) | 6.25 (±2.74) | 0.323 |
Sex, female (n) | 86 | 56 | 36 | 0.285 |
Education (years), median (range) | 8 (2–18) | 8 (3–18) | 8 (2–18) | 0.121 |
MMSE at first visit, mean (sd) | 21.92 (±4.54) | 21.48 (±5.03) | 22.60 (±3.57) | 0.149 |
MMSE at recruitment, mean (sd) | 16.51 (±8.42) | 15.91 (±8.84) | 17.50 (±7.67) | 0.376 |
Early anosognosia (CIRS); median | 3 | 3 | 4 | 0.503 |
Current anosognosia (CIRS), median | 6 | 6 | 6 | 0.947 |
Mean time between first assessment and recruitment (months, sd) | 42.68 (±33.42) | 36.07 (±30.70) | 52.87 (±35.11) | 0.003 |
Current NPI total, median (range) | 14 (0–57) | 15 (0–54) | 14 (0–57) | 0.802 |
CIRS, Clinical Insight Rating Scale; NPI, Neuropsychiatry Inventory; MMSE, Mini Mental State Examination; sd, standard deviation; ns, not significant.