Table 3.
Observed and expected-by-chance KIR/HLA-C combinations.
| Uncomplicated (n=309) | P-value* Observed vs Expected | Preeclampsia (n=49) | P-value* Observed vs Expected | P-value* Uncomplicated vs Preeclampsia (observed only) | |||
|---|---|---|---|---|---|---|---|
| Observed (%) | Expected (%) | Observed (%) | Expected (%) | ||||
| Genotype | 0.292 | ||||||
| KIR AA/HLA C1 | 20.1 | 21.7 | 0.465 | 20.4 | 17.7 | 0.956 | |
| KIR AA/HLA C2 | 15.9 | 14.2 | 22.4 | 21.1 | |||
| KIR Bx/HLA C1 | 65.4 | 65.4 | 59.2 | 61.9 | |||
| KIR Bx/HLA C2 | 45.3 | 45.0 | 53.1 | 54.4 | |||
| Paternally inherited C1/C2 only | 0.045 | ||||||
| KIR AA/HLA C1 | 14.6 | 14.5 | 1.000 | 10.2 | 8.8 | 0.977 | |
| KIR AA/HLA C2 | 9.7 | 9.8 | 16.3 | 17.7 | |||
| KIR Bx/HLA C1 | 46.6 | 46.7 | 38.8 | 40.1 | |||
| KIR Bx/HLA C2 | 29.1 | 29.0 | 34.7 | 33.3 | |||
*P-values calculated by Chi-square analysis. P-values are corrected for multiple comparisons with the Bonferroni method. p < 0.05 is considered significant.