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. 2021 May 13;12:669215. doi: 10.3389/fgene.2021.669215

TABLE 2.

Identified novel variants with genome-wide significant associations.

SNP Nearest gene Trait Chromosome position Minor allele MAF Discovery (n = 2,869)
Replication (n = 37,321)
Combination (n = 40,169)
β ± SE P value β ± SE P value β ± SE P value
rs1307273 RP11-513I15.6 Height–women 6:34240886 G 0.205 0.82 ± 0.17 9.27 × 10–7 0.33 ± 0.04 5.19 × 10–14 0.37 ± 0.04 3.37 × 10–17
rs9469757 RP11-513I15.6 Height–women 6:34232864 C 0.170 0.87 ± 0.18 1.16 × 10–6 0.37 ± 0.05 1.41 × 10–14 0.40 ± 0.05 3.10 × 10–17
rs1759637 RP11-513I15.6 Height–women 6:34237130 C 0.193 0.82 ± 0.17 1.62 × 10–6 0.32 ± 0.05 4.49 × 10–12 0.35 ± 0.04 8.54 × 10–15
rs7133285 RP11-977G19.10 Height–women 12:56699429 A 0.232 −0.75 ± 0.16 2.25 × 10–6 −0.67 ± 0.04 2.27 × 10–54 −0.67 ± 0.04 4.19 × 10–58
rs9469761 RP11-513I15.6 Height–women 6:34236429 A 0.169 0.85 ± 0.18 2.53 × 106 0.37 ± 0.05 1.38 × 1014 0.40 ± 0.05 3.25 × 1017
rs1776890 RP11-513I15.6 Height–women 6:34237747 G 0.194 0.79 ± 0.17 3.62 × 106 0.32 ± 0.05 9.86 × 1013 0.35 ± 0.04 1.51 × 1015
rs13207853 RP11-513I15.6 Height–women 6:34238946 C 0.181 0.81 ± 0.18 4.64 × 106 0.33 ± 0.05 1.57 × 1012 0.37 ± 0.05 1.59 × 1015
rs2797961 RP11-513I15.6 Height–women 6:34237797 G 0.205 0.77 ± 0.17 4.67 × 106 0.32 ± 0.04 6.31 × 1013 0.35 ± 0.04 9.07 × 1016
rs200808496 RP11-513I15.6 Height–women 6:34237376 T 0.203 0.75 ± 0.17 7.40 × 106 0.31 ± 0.04 9.98 × 1012 0.33 ± 0.04 5.34 × 1014

Age and residential area were included as covariants in all genetic models. Variants stated in the manuscript are indicated in bold. MAF, minor allele frequency; β, regression coefficient; SE, standard error; N, the number of participants included in each stage.