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. 2021 May 13;8:671263. doi: 10.3389/fmolb.2021.671263

TABLE 5.

Representative therapeutic antibodies strategies for CoV infections.

Name of drugs Mechanism of action In vitro In vivo Clinical trial Approved References
Dexamethasone Prevents the release of substances in the body that cause inflammation N.A. N.A. SARS-CoV-2 Prevents inflammation Recovery Collaborative Group et al., 2020; Atyeo et al., 2021
Tocilizumab Anti-IL-6 N.A. N.A. SARS-CoV-2 Adult patients with active rheumatoid arthritis Stone et al., 2020
Sarilumab Anti-IL-6R N.A. N.A. SARS-CoV-2 Moderates to severe active rheumatoid arthritis Castelnovo et al., 2021