TABLE 5.
Representative therapeutic antibodies strategies for CoV infections.
| Name of drugs | Mechanism of action | In vitro | In vivo | Clinical trial | Approved | References |
| Dexamethasone | Prevents the release of substances in the body that cause inflammation | N.A. | N.A. | SARS-CoV-2 | Prevents inflammation | Recovery Collaborative Group et al., 2020; Atyeo et al., 2021 |
| Tocilizumab | Anti-IL-6 | N.A. | N.A. | SARS-CoV-2 | Adult patients with active rheumatoid arthritis | Stone et al., 2020 |
| Sarilumab | Anti-IL-6R | N.A. | N.A. | SARS-CoV-2 | Moderates to severe active rheumatoid arthritis | Castelnovo et al., 2021 |