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. 2021 May 27;11:323. doi: 10.1038/s41398-021-01419-2

Table 2.

Association of the factors with group membership (n = 1207): hierarchical multinomial regression.

OCS+/OCS+b OCS−/OCS+b OCS+/OCS−b
Variables OR [CI 95%] p OR [CI 95%] p OR [CI 95%] p
Block 1
Age 0.994 [0.978, 1.011] 0.490 1.005 [0.989, 1.022] 0.528 0.985 [0.964, 1.006] 0.167
Education (A levels) 1.085 [0.606, 1.943] 0.785 1.007 [0.507, 2.000] 0.983 0.388 [0.165, 0.912] 0.030
Sex (1 = f, 2 = m) 1.825 [1.218, 2.733] 0.004 0.925 [0.587, 1.457] 0.735 1.992 [1.088, 3.646] 0.026
PHQ-9, t0 1.066 [0.996, 1.141] 0.067 1.005 [0.935, 1.080] 0.892 1.002 [0.898, 1.119] 0.968
C-OCS, t0a 31.931 [11.923, 85.514] <0.001 5.266 [1.246, 22.265] 0.024 8.176 [2.112, 31.644] 0.002
nC-OCS, t0a 11.416 [4.962, 26.269] <0.001 8.836 [3.747, 20.835] <0.001 1.905 [0.271, 13.377] 0.517
Block 2
Age 0.998 [0.981, 1.016] 0.850 1.002 [0.985, 1.020] 0.806 0.984 [0.963, 1.006] 0.153
Education (A levels) 0.962 [0.486, 1.904] 0.912 0.998 [0.493, 2.021] 0.996 0.348 [0.144, 0.845] 0.020
Sex (1 = f, 2 = m) 1.746 [1.093, 2.788] 0.020 1.045 [0.652, 1.674] 0.856 2.222 [1.204, 4.102] 0.011
PHQ-9, t0 1.062 [0.989, 1.141] 0.099 1.021 [0.956, 1.090] 0.544 0.995 [0.895, 1.106] 0.925
C-OCS, t0a 20.633 [6.495, 65.548] <0.001 3.185 [0.726, 13.969] 0.125 8.142 [2.093, 31.670] 0.002
nC-OCS, t0a 8.962 [3.529, 22.754] <0.001 7.363 [2.956, 18.340] <0.001 1.644 [0.231, 11.719] 0.620
AAQ-OCD-COVID, t1 1.145 [1.120, 1.172] <0.001 1.074 [1.050, 1.098] <0.001 1.064 [1.035, 1.094] <0.001
Change in AAQ-OCD-COVID, t1–t2 0.934 [0.911, 0.957] <0.001 0.922 [0.900, 0.945] <0.001 1.017 [0.981, 1.055] 0.356

aReference group: no OCS (total score at t0 <18).

bReference group: asymptomatic trajectory (OCS−/OCS−); after adjustment for multiple testing according to the Holm-Bonferroni procedure, only findings with a p of .001 or below should be considered statistically significant.

OCS obsessive-compulsive symptoms, OR Odds ratio, OCS+/OCS+ continuously symptomatic trajectory with OCS at t1 and t2, OCS−/OCS+ delayed onset trajectory without OCS at t1 but at t2, OCS+/OCS− the recovery group trajectory with OCS at t1 but not at t2, C-OCS contamination-related OCS (OCI-R total score at t0 ≥18 and washing subscale at t0 ≥3), nC-OCS contamination-unrelated OCS (OCI-R total score at t0 ≥18 and washing subscale at t0 <3), PHQ-9 the Patient Health Questionnaire Depression Module, OCI-R Obsessive-Compulsive Inventory-Revised, AAQ-OCD-COVID Acceptance and Action Questionnaire for Obsessions and Compulsions (COVID-19 adaption).