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. Author manuscript; available in PMC: 2021 Oct 9.
Published in final edited form as: Hepatology. 2020 Oct 9;72(4):1298–1309. doi: 10.1002/hep.31146

Table 1.

Baseline characteristics of matched statin users and statin non-user in all ECC cases and all controls

Variable All ECC All controls

Statin user (N=73) Statin non-user (N=321) p-value Statin user (N=403) Statin non-user (N=385) p-value

Age in years, mean (SD) 69.3 (10.9) 64.9 (14.3) 0.014 65.9 (12.4) 65.2 (15.0) 0.98

Sex, male 57 (78.1%) 211 (65.7%) 0.041 297 (73.7%) 241 (62.6%) <0.001

Race 0.082 0.015
White, n (%) 73 (100.0%) 307 (95.6%) 395 (98.0%) 365 (94.8%)
Non-white, n (%) 0 (0.0%) 14 (4.4%) 8 (2.0%) 20 (5.2%)

BMI; mean (SD) 29.1 (5.4) 27.5 (6.1) 0.005 29.5 (4.9) 28.1 (5.5) <0.001

DM, n (%) 39 (53.4%) 84 (26.2%) <0.001 209 (51.9%) 94 (24.4%) <0.001

IBD, n (%) 2 (2.7%) 39 (12.1%) 0.017 7 (1.7%) 4 (1.0%) 0.40

Cirrhosis, n (%) 8 (11.0%) 67 (20.9%) 0.068 34 (8.4%) 25 (6.5%) 0.30

Cholangitis, n (%) 27 (37%) 86 (26.8%) 0.087 1 (0.2%) 0 (0.0%) 0.33

PSC, n (%) 11 (15.1%) 114 (35.5%) 0.005 0 (0.0%) 0 (0.0%) 1.00

HCV, n (%) 2 (2.7%) 19 (5.9%) 0.39 5 (1.2%) 1 (0.3%) 0.11

Other liver disease, n (%) 3 (4.1%) 36 (11.2%) 0.081 11 (2.7%) 10 (2.6%) 0.91

CAD, n (%) 44 (60.3%) 69 (21.5%) <0.001 209 (51.9%) 49 (12.7%) <0.001

Stroke, n (%) 6 (8.2%) 1 (0.3%) <0.001 105 (26.1%) 27 (7.0%) <0.001

Smoking, n (%) 16 (5.71%) 58 (20.7%) 0.07 199 (25.4%) 175 (22.3%) 0.27

Alcohol use, n (%) 25 (8.93%) 101 (36.1%) 0.04 309 (39.4%) 287 (36.6%) 0.38