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. 2021 May 13;12:624655. doi: 10.3389/fpsyg.2021.624655

TABLE 1.

Summary of studies with slow-paced breathing that target variables that are relevant in the context of the COVID-19 pandemic.

Study Relevant dependent variable Relevant findings with effect sizes1 Biofeedback Target population Sample size
Bernardi et al., 2001 Hypoxia, hypercapnia, and baroreflex sensitivity SPB reduced the chemoreflex response to both hypoxia and hypercapnia No Healthy adults 15
Bernardi et al., 1998 Oxygen saturation and exercise performance SPB reduced dyspnea and improved both resting pulmonary gas exchange and exercise performance No Chronic heart failure patients and healthy adults 61
Bilo et al., 2012 Ventilation efficiency for oxygen SPB increased blood oxygenation and reduced systemic and pulmonary arterial pressure No Healthy adults Experiment 1: 39; Experiment 2: 28
Laborde et al., 2019a SSQ and CVA SPB increased subjective sleep quality (d = 0.51) and increased overnight-CVA (d = 0.68) as well as morning-CVA (d = 0.42) No Healthy adults 64
Laborde et al., 2019b Adaptation to psychological stress after physical exertion and CVA SPB led to better Stroop interference accuracy (ηp2 = 0.170) after physical exertion No Young adults Experiment 1: 60; Experiment 2: 60
Laborde et al., 2016 CVA CVA was higher during SPB compared to control (d = 0.35) No Adolescents with intellectual disability 17
Paul and Garg, 2012 Anxiety, CVA, and sports performance SPB reduced both trait and state anxiety, increased CVA (HF), and increased sports performance (dribbling, shooting, and passing) Yes Basketball players 30
Pusenjak et al., 2015 Self regulation (heart rate, galvanic skin response, and coherence) HR during stress tasks was better in SPB group than control. Yes Athletes 39
Wells et al., 2012 CVA and stress reaction SPB after stressor increased HF (ηp2 = 0.122) Yes Trained musicians 45

Notes. 1Wherever reported. CVA, cardiac vagal activity; SPB, Slow-paced breathing; SSQ, Subjective sleep quality; HRV, Heart rate variability; and HF, High frequency.