TABLE 1.
Cytokines | Producing cells | Function | References |
---|---|---|---|
IL-12 | monocytes, macrophages,DCs,B cells | Th1 differentiation; Th2 inhibition; IFN-γ↑ | Wu et al. 2016 |
IL-23 | monocytes, macrophages,DCs,B cells, endothelial cells | Th17 differentiationIL-17↑ ; Proliferation of CD4+ memory T cells | Nakano et al. 2015b |
IL-27 | macrophages,DCs,B cells | Inhibition of immune system responses; limit the inflammatory | Behzadi et al. 2016 |
IL-35 | Tregs, breg, endothelial cells; monocytes | Treg and breg differentiation; iTR35 differentiation; Th17 inhibition; teff inhibition; IL-35 and IL-10 ↑; M1macrophages↓; M2macrophages↑ | Choi et al. 2015 |