Figure 7.
Regulatory effect of LncRNA SNHG3 on the proliferation and metastasis of lung cancer cells through miR-515-5p/SUMO2. A, CCK-8 detection of the inhibitory effect of miR-515-5p or SUMO2 siRNA on the cell proliferation-promoting of overexpressing SNHG3 in lung cancer H1270 cells. B and C, Transwell detection of the inhibitory effect of miR-515-5p or SUMO2 siRNA on the cell migration-promoting of overexpressing SNHG3 in lung cancer H1270 cells (Magnification, 200×; Scale bar, 50 µm). D, Western blot detection of the effect of overexpressing SNHG3 and simultaneous transfection of miR-515-5p or SUMO2 siRNA on the expression of EMT related proteins in lung cancer H1270 cells. *P < 0.05, **P < 0.01 versus control.