Illustration of the contact positions of antibody and ACE2 epitopes with SARS-CoV-2 and SARS-CoV S-protein RBDs on RBD 2D sequences. The proteins in the structures of 6M0J, 6WPS, 6W41, 7C01, 7BWJ, 7BZ5, 6Z43, and 7BYR are in complexes with the SARS-CoV-2 S protein, while the proteins in the structures of 3D0G, 2DD8, 6NB6, 6WAQ, 2GHW, and 3BGF are in complexes with the SARS-CoV S protein. Abbreviations: ACE2, angiotensin-converting enzyme 2; RBD, receptor-binding domain; S, spike; SARS-CoV, severe acute respiratory syndrome coronavirus.