Table 4.

Summary of ongoing clinical trials of COVID-19 antibody therapeutic candidates

Antibody ID	Manufacturer	Target	Trial location	Trial phase	Start date
Lanadelumab^a	Shire	pKal	Radboud University Medical Center, Nijmegen, Netherlands	4	/
Octagam^a	Pfizer	Antibody mixture	Sharp Memorial Hospital, San Diego, California, United States	4	4/28/2020
Sarilumab^a,b	Regeneron Pharmaceuticals and Sanofi	IL-6	Assistance Publique—Hôpitaux de Paris, Paris, France	3	3/25/2020
Sarilumab^a,b	Regeneron Pharmaceuticals and Sanofi	IL-6	VA Boston Healthcare System, Boston, Massachusetts, United States	2	4/10/2020
Sirukumab^a,b	Janssen Biotech	IL-6	Sanofi-Aventis Recherche et Développement, Chilly-Mazarin, France	3	3/26/2020
Sirukumab^a,b	Janssen Biotech	IL-6	Loyola University Medical Center, Maywood, Illinois, United States	2	4/24/2020
Canakinumab^a,b	Novartis	Interleukin-1β	Novartis Investigative Site, Glendale, California, United States	3	4/30/2020
Canakinumab^a,b	Novartis	Interleukin-1β	Novartis Pharma GmbH, Nürnberg, Germany	3	4/29/2020
IFX-1^b	InflaRx	C5a	InflaRx GmbH, Jena, Germany	3	3/29/2020
Lenzilumab^a	Humanigen	GM-CSF	Mayo Clinic, Phoenix, Arizona, United States	3	4/30/2020
Mylotarg^b	Celltech and Wyeth	CD33	UK Research and Innovation, United Kingdom	3	5/5/2020
Ravulizumab^b	Alexion Pharmaceuticals	C5	Alexion Europe SAS, Levallois-Perret, France	3	5/7/2020
Tocilizumab^a,b	Roche	IL-6	Queen’s Medical Center, Honolulu, Hawaii, United States	3	6/1/2020
Tocilizumab^a,b	Roche	IL-6	F. Hoffmann-La Roche Ltd., Basel, Switzerland	3	4/6/2020
Avdoralimab^b	Innate Pharma	C5a	Assistance Publique Hôpitaux De Marseille, Marseille, France	2	4/23/2020
Bevacizumab^b	Genentech	VEGF-A	Fundación para la Investigación Biomédica de Córdoba, Córdoba, Spain	2	4/24/2020
CERC 002^a	Cerecor	LIGHT	Cape Fear Valley Medical Center, Fayetteville, North Carolina, United States	2	6/9/2020
Clazakizumab^a	Bristol Myers Squibb and Alder Biopharmaceuticals	IL-6	Cedars-Sinai Medical Center, Los Angeles, California, United States	2	4/24/2020
Gimsilumab^a	Eisai Inc	GM-CSF	UCLA Ronald Reagan Medical Center, Los Angeles, California, United States	2	4/12/2020
IC14^a	Scripps Research	CD14	University of Washington, Seattle, Washington, United States	2	7/2020
Infliximab^a	Janssen Biotech	TNFα	Tufts Medical Center, Boston, Massachusetts, United States	2	6/1/2020
Leronlimab^a	CytoDyn	CCR5	University of California, Los Angeles, California, United States	2	4/1/2020
LY3127804^a	Eli Lilly and Company	Ang2	NorthShore University HealthSystem, Evanston, Illinois, United States	2	4/20/2020
LY3819253^a	Eli Lilly and Company	S protein	Cedars-Sinai Medical Center, Los Angeles, California, United States	2	6/13/2020
Mavrilimumab^a	MedImmune	GM-CSF	Cleveland Clinic Health System, Cleveland, Ohio, United States	2	5/20/2020
MSTT1041A^a	Genentech	ST2	eStudySite-Chula Vista-PPDS, Chula Vista, California, United States	2	6/2/2020
Nivolumab^b	Bristol-Myers Squibb	PD-1	Centre Léon Bérard, Léon, France	2	4/1/2020
Otilimab^a,b	MorphoSys	GM-CSF	GSK Investigational Site, Saint Louis Park, Minnesota, United States	2	5/28/2020
Otilimab^a,b	MorphoSys	GM-CSF	GlaxoSmithKline Research Development Ltd., Brentford, United Kingdom	2	5/20/2020
Siltuximab^b	Eusapharma	IL-6	Fundacié Clínic per a la Recerca Biomédica, Barcelona, Spain	2	4/7/2020
SNDX-6352^a	Syndax Pharmaceuticals	CSF-1R	HonorHealth, Scottsdale, Arizona, United States	2	5/30/2020
ARGX-117^b	Argenx	C2	Argenx BV, Zwijnaarde, Belgium	1	4/21/2020
TJ003234^a	/	GM-CSF	GW Medical Faculty Associates, Washington, District of Columbia, United States	1	4/11/2020
JS016^c	Junshi Biosciences	S protein	Huashan Hospital Affiliated to Fudan University, Shanghai, China	1	6/7/2020

See https://clinicaltrials.gov/ct2/results?recrs=ab&cond=covid-19&term=&cntry=US&state=&city=&dist=.

See https://www.clinicaltrialsregister.eu/ctr-search/search?query=covid-19.

See https://www.globenewswire.com/news-release/2020/06/07/2044620/0/en/Junshi-Biosciences-Announces-Dosing-of-First-Healthy-Volunteer-in-Phase-I-Clinical-Study-of-SARS-CoV-2-Neutralizing-Antibody-JS016-in-China.html.