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. 2021 May 26;4(5):e2111582. doi: 10.1001/jamanetworkopen.2021.11582

Table. Characteristics of the Included Studies.

Study Intervention group [dropouts at last follow-up] Control group [dropouts at last follow-up] Treatment frequency and duration Follow-up Outcome measures Difference of means (favors HBP or IOP)
Akkaya et al,36 2012 EBT (group A) and NEMS + HBP (group B) combined for meta-analysis (n = 30) [none] HBP (n = 15); duration: 1 mo [none] I: 5 d/wk for the first 2 wk post-op; C: 1 mo 6 wk (short-term) Lysholm score 6.2 (IOP)
6 wk (short-term) Knee flexion 8.2° (IOP)
6 wk (short-term) Knee extension 0.9° (HBP)
6 wk (short-term) Thigh girth 0.7 cm (HBP)
Forster and Frost,23 1982 Outpatient PT + HBP (n = 44) [1] HBP (n = 42) [1] I: 3 times/wk for 4 wk, start on the 12th postop d (duration by clinical judgment); C: not specified 6 wk (short-term) Knee flexion 0.9° (IOP)
6 wk (short-term) Thigh girth 0.4 cm (IOP)
Absolute data DRW 4 d (HBP)
Goodwin et al,37 2003a Supervised PT + HBP (n = 44) [5] HBP (n = 40) [10] I: 3 times/wk for 6 wk; C: 6 wk 50 d (short-term) Single hop 11.9 cm (IOP)
50 d (short-term) Vertical hop 3.47 cm (IOP)
Absolute data DRW 12.6 d (HBP)
Hadley et al,38 2019 Outpatient PT (n = 46) [not indicated] Internet-based rehabilitation (n = 51) [not indicated] I: 2 sessions/wk for 4-6 wk; C: minimum 3 times/wk (duration not specified) 6 wk (short-term) Lysholm score 6.5 (IOP)
6 mo (midterm) Lysholm score 5.67 (IOP)
6 wk (short-term) IKDC 4.6 (IOP)
Kelln et al,39 2009b Active RoM recovery on a bicycle ergometer + HBP (n = 16) [2] HBP (n = 15) [1] I: 3 times/wk (duration not specified); C; duration not specified 1 mo (short-term) IKDC 9.6 (IOP)
1 mo (short-term) Knee flexion 12.2° (IOP)
1 mo (short-term) Knee extension 0.5° (HBP)
1 mo (short-term) Thigh girth 1.9 cm (HBP)
Kirnap et al,40 2005 EMG biofeedback training + HBP (n = 20) [none] HBP (n = 20), duration 1 mo [none] I + C: 5 times/wk for 2 wk 6 wk (short-term) Lysholm score 15.8 (IOP)
6 wk (short-term) Knee flexion 7.9° (IOP)
Moffet et al,41 1994 Outpatient PT + HBP (n = 15) [1] HBP (n = 16) [none] I + C: 3 wk 3 mo (short-term) Lysholm score 3 (IOP)
6 mo (midterm) Lysholm score 2 (IOP)
Vervest et al,42 1990 Exercise-based outpatient PT (n = 10) [none] HBP + verbal and written advice (n = 10) [none] I: 30-min sessions for 3 wk; C: duration not specified 28 d (short-term) Lysholm score 9.3 (IOP)
28 d (short-term) Single hop 19.1 cm (IOP)
28 d (short-term) Vertical hop 2.4 cm (IOP)

Abbreviations: C, control group; DRW, days to return to work; EBT, electromyography biofeedback therapy; HBP, home-based program; I, intervention group; IKDC, subjective International Knee Documentation Committee score; IOP, inpatient and/or outpatient rehabilitation; NEMS, neuromuscular electrical stimulation; PT, physical therapy; RoM, range of motion.

a

Data retrieved contacting the authors.

b

Data extracted from plots via WebPlotDigitizer version 4.3 (Ankit Rohatgi).