Skip to main content
. 2021 May 17;22(10):5276. doi: 10.3390/ijms22105276

Table 1.

Overview of proteins involved in sarcolemma repair.

Protein Symbol Function Binding Partners Ref
Annexin A1 ANXA1 The “lipid patch” formation DYSF, S100A11 [40,41,42,43]
Annexin A2 ANXA2 The “lipid patch” formation DYSF, S100A10 [40,41,42,43]
Annexin A4 ANXA4 To be established To be identified [44]
Annexin A5 ANXA5 Strengthening the damaged membrane To be identified [24,45]
Annexin A6 ANXA6 Condensing membranes at the disruption site To be identified [26,29,46,47]
Annexin A7 ANXA7 To be established To be identified [48,49]
Anoctamin-5 ANO5 To be established To be identified [50,51,52,53,54]
Calpains CAPN1-3 The formation of mini-dysferlinc72 DYSF [55,56,57,58]
Caveolin-3 CAV3 Controlling membrane tension DYSF, MG53 [59,60,61,62,63,64,65]
Dysferlin DYSF Recruiting the “lipid patch” ANXA1, ANXA2, Calpains, CAV3, MG53 [8,9,40,46,55,59,66,67,68,69,70]
Mitsugumin-53 MG53 Strengthening the damaged membrane and recruiting the “lipid patch” DYSF, CAV3 [65,70,71]