Skip to main content
. 2021 May 15;9(5):553. doi: 10.3390/biomedicines9050553

Figure 2.

Figure 2

Pre- and postoperative serum biomarker profiling (no-POD and POD). Serum was sampled prior to (A) and following surgery (B) from a mixed cohort of consecutively recruited elective non-cardiac, as well as cardiac surgery patients. Biomarker profiling was performed using the multiplex array technique. The whole cohort was divided according to development of postoperative delirium (POD). Data are given as median values (black dashed line) with 25th and 75th percentile (white dashed lines) and were compared using the Mann-Whitney U test. no POD: n = 85, POD: n = 33. ns = not significant, * p < 0.05. E-Sel = E-Selectin, ICAM-1 = Intercellular Adhesion Molecule 1, VCAM-1 = Vascular Cell Adhesion Protein 1, SDC1 = Syndecan-1, THBD = Thrombomodulin, ANGPT2 = Angiopoietin-2, TIE2 = Tyrosine Kinase with Immunoglobulin-like and EGF-like domains 2, IL-8 = Interleukin-8, CCL2 = CC-chemokine Ligand 2, RAGE = Receptor for Advanced Glycation Endproducts, CXCL5 = C-X-C Motif Chemokine 5, uPAR = Urokinase Plasminogen Activator Surface Receptor, and NSE = Neuron-specific Enolase.