| IVD | intervertebral disc |
| ATP | adenosine triphosphate |
| HIF-1α | hypoxia-inducible factor-1 alpha |
| NP | nucleus pulposus |
| AF | annulus fibrosus |
| CEP | cartilaginous end plate |
| GAG | anionic glycosaminoglycan |
| PHD | prolyl 4-hydroxylase domain-containing |
| VHL | von Hippel–Lindau tumor suppressor |
| HRE | hypoxia responsive element |
| FIH-1 | factor inhibiting HIF-1 |
| C-TAD | C-transactivation domains |
| FasL | Fas ligand |
| ECM | extracellular matrix |
| GLUT | glucose transporter |
| ANK | ankylosis protein homolog gene |
| VEGF | vascular endothelial growth factor |
| VEGFR | vascular endothelial growth factor receptor |
| AMPK | adenosine 5′-monophosphate-activated protein kinase |
| mTOR | mechanistic target of rapamycin |