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A summary of epidermal neural crest stem cells (EPI-NCSCs) characterization (A), benefit in a rat model of ischemic stroke (B), pretreatment with small molecules (C) and biomaterial assistance (D). DCX: doublecortin, GFAP: glial fibrillary acidic protein, BDNF: brain-derived neurotrophic factor, VPA: valproic acid, GDNF: glial cell-derived neurotrophic factor, VEGF: vascular endothelial growth factor, DMF: dimethyl fumarate, NT3: neurotrophin-3.
