Table 1.

Docking score of binding of S-RBD region of different novel variants with neutralizing CV30 antibody and hACE2.

	CV30/Spike						hACE2/Spike
Rank	* WT	B.1.1.7	B.1.351	P.1	E484K	B.1.617	* WT	B.1.1.7	B.1.351	E484K	B.1.617
Docking Score	−371.61	−337.93	−260.34	−270.72	−263.21	−269.54	−310.19	−353.32	−266.76	−323.78	−341.31
Ligand RMSD (Å2)	2.32	142.44	324.79	385.41	74.78	384.23	3.27	0.79	93.91	0.56	0.36
Score Affinity %	100	90.93	70.05	72.85	70.82	72.53	100	113.9	85.99	104.38	110.03

* Wild-type (WT) data was considered with a 100% index, and data mutations were measured according to this criterion.