Table 4.
Antibiotic | Costs in Millions | % Difference 2020–2018 (p-Value) * |
% Difference2020–2019 (p-Value) * |
||
---|---|---|---|---|---|
2018 | 2019 | 2020 | |||
Amoxicillin | 4.12 | 4.49 | 4.26 | 3.18 (0.482) | −5.22 (0.277) |
Phenoxymethylpenicillin | 7.46 | 5.43 | 3.86 | −48.21 (0.006) | −28.90 (0.018) |
Co-amoxiclav | 1.82 | 1.87 | 2.04 | 11.90 (0.013) | 9.03 (0.064) |
Benzylpenicillin | 0.004 | 0.002 | 0.002 | −57.59 (0.025) | −17.33 (0.085) |
Flucloxacillin | 11.24 | 11.29 | 8.13 | −27.70 (0.002) | −28.05 (0.002) |
Cefalexin | 0.73 | 0.78 | 1.06 | 45.78 (0.002) | 36.27 (0.002) |
Ceftriaxone | 0.08 | 0.06 | 0.05 | −36.85 (0.006) | −15.70 (0.085) |
Ciprofloxacin | 0.90 | 0.84 | 0.86 | −4.90 (0.482) | 2.50 (0.620) |
Ofloxacin | 0.78 | 0.72 | 0.87 | 12.58 (0.004) | 20.61 (0.003) |
Doxycycline | 1.75 | 2.38 | 4.16 | 137.37 (0.002) | 74.61 (0.002) |
Clarithromycin | 2.81 | 2.81 | 3.00 | 6.54 (0.482) | 6.74 (0.277) |
Clindamycin | 1.12 | 0.82 | 0.87 | −22.06 (0.002) | 6.45 (0.003) |
Nitrofurantoin | 20.91 | 20.96 | 20.81 | −0.489 (0.949) | −0.75 (0.902) |
Trimethoprim | 1.59 | 1.78 | 1.82 | 14.62 (0.064) | 2.70 (1.000) |
Metronidazole oral | 1.68 | 2.08 | 4.25 | −5.74 (0.655) | −23.87 (0.001) |
Metronidazole ointment | 2.11 | 2.19 | 3.86 | −16.86 (0.655) | −19.98 (0.001) |
Vancomycin | 0.57 | 0.50 | 2.04 | −13.64 (0.225) | −1.48 (0.710) |
Fusidic acid | 1.33 | 1.62 | 0.002 | 33.24 (0.002) | 8.93 (0.142) |
Mupirocin | 0.24 | 0.23 | 8.12 | −18.78 (0.003) | −18.20 (0.002) |
Chloramphenicol | 1.24 | 1.79 | 1.07 | 52.88 (0.003) | 6.19 (0.001) |
All antibiotics | 62.08 | 62.58 | 59.34 | −4.42% (0.180) | −5.18 (0.097) |
* p-Values calculated using Mann–Whitney U-tests.