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. 2021 May 17;10(5):591. doi: 10.3390/antibiotics10050591

Table 4.

Costs (in millions) of the antibiotics prescribed between March and September in 2018–2020.

Antibiotic Costs in Millions % Difference 2020–2018
(p-Value) *
% Difference2020–2019
(p-Value) *
2018 2019 2020
Amoxicillin 4.12 4.49 4.26 3.18 (0.482) −5.22 (0.277)
Phenoxymethylpenicillin 7.46 5.43 3.86 −48.21 (0.006) −28.90 (0.018)
Co-amoxiclav 1.82 1.87 2.04 11.90 (0.013) 9.03 (0.064)
Benzylpenicillin 0.004 0.002 0.002 −57.59 (0.025) −17.33 (0.085)
Flucloxacillin 11.24 11.29 8.13 −27.70 (0.002) −28.05 (0.002)
Cefalexin 0.73 0.78 1.06 45.78 (0.002) 36.27 (0.002)
Ceftriaxone 0.08 0.06 0.05 −36.85 (0.006) −15.70 (0.085)
Ciprofloxacin 0.90 0.84 0.86 −4.90 (0.482) 2.50 (0.620)
Ofloxacin 0.78 0.72 0.87 12.58 (0.004) 20.61 (0.003)
Doxycycline 1.75 2.38 4.16 137.37 (0.002) 74.61 (0.002)
Clarithromycin 2.81 2.81 3.00 6.54 (0.482) 6.74 (0.277)
Clindamycin 1.12 0.82 0.87 −22.06 (0.002) 6.45 (0.003)
Nitrofurantoin 20.91 20.96 20.81 −0.489 (0.949) −0.75 (0.902)
Trimethoprim 1.59 1.78 1.82 14.62 (0.064) 2.70 (1.000)
Metronidazole oral 1.68 2.08 4.25 −5.74 (0.655) −23.87 (0.001)
Metronidazole ointment 2.11 2.19 3.86 −16.86 (0.655) −19.98 (0.001)
Vancomycin 0.57 0.50 2.04 −13.64 (0.225) −1.48 (0.710)
Fusidic acid 1.33 1.62 0.002 33.24 (0.002) 8.93 (0.142)
Mupirocin 0.24 0.23 8.12 −18.78 (0.003) −18.20 (0.002)
Chloramphenicol 1.24 1.79 1.07 52.88 (0.003) 6.19 (0.001)
All antibiotics 62.08 62.58 59.34 −4.42% (0.180) −5.18 (0.097)

* p-Values calculated using Mann–Whitney U-tests.