Skip to main content
. 2021 May 27;57(5):2002559. doi: 10.1183/13993003.02559-2020

FIGURE 1.

FIGURE 1

Schematic of the study design and CONSORT (Consolidated Standards of Reporting Trials) diagrams. PK: pharmacokinetics; BAL: bronchoalveolar lavage; PD: pharmacodynamics. a) Part 1 (healthy subjects). Each single-dose cohort consisted of six healthy subjects randomised 4:2 to active and placebo. A minimum of five patients’ data was required in each cohort prior to data review. b) CONSORT diagram for part 1. c) Part 2 (idiopathic pulmonary fibrosis patients). Each repeat-dose cohort consisted of eight subjects randomised 5:3 to active and placebo. A minimum of seven patients’ data was required in each cohort prior to data review. d) CONSORT diagram for part 2.