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Genetic determinants of MAFLD influence response to the nutrients. PNPLA3, Phospholipase domain-containing protein-3; MBOAT7, Membrane-bound O-acyltransferase domain containing 7; TM6SF2, Transmembrane 6 superfamily member 2 protein; GCKR, Glucokinase regulator; SREBP1, Sterol regulatory element-binding proteins; VLD, Very-low-density lipoproteins; FAs, Fatty acids.
