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. 2021 May 14;26(10):2917. doi: 10.3390/molecules26102917

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The proposed targets and related therapeutic candidates in SARS-CoV-2. Atg: autophagy-related; CAT: catalase; CQ: chloroquine; HCQ: hydroxyl chloroquine; GST-1 α: glutathione s-transferases-1α; HO-1: heme oxygenase; IFN: interferon; IL: interleukin; JAK/STAT: Janus kinase (JAK)/signal transducer and activator of transcription (STAT); LC3: light chain 3; NF-κB: nuclear factor kappa B; ROS: reactive oxygen species; RTK: receptor tyrosine kinase; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; SOD: superoxide dismutase; TNF-α: tumor necrosis factor-α.