Table 2.
Antifungal activity of Bupleurum rigidum subsp. paniculatum essential oil.
| Strains | Essential Oil | Fluconazole | ||
|---|---|---|---|---|
| MIC | MLC | MIC | MLC | |
| Candida albicans ATCC 10231 | 576 | 576 | 1 | >128 |
| Candida tropicalis ATCC 13803 | 1125 | 1125 | 4 | >128 |
| Candida krusei H9 | 288 | 288 | 64 | 64–128 |
| Candida guillermondii MAT23 | 288 | 288 | 8 | 8 |
| Candida parapsilosis ATCC 90018 | 576 | 576 | 1 | 1–2 |
| Cryptococcus neoformans CECT 1078 | 72 | 144 | 16 | 128 |
| Trichophytum mentagrophytes FF7 | 288 | 288 | 16–32 | 32–64 |
| Trichophytum mentagrophytes var. interdigitale CECT 2958 | 288 | 288 | 128 | ≥128 |
| Trichophyton rubrum CECT 2794 | 72 | 72 | 16 | 64 |
| Trichophytum verrucosum CECT 2992 | 288 | 288 | 128 | >128 |
| Microsporum canis FF1 | 144 | 144 | 128 | 128 |
| Microsporum gypseum CECT 2905 | 288 | 288 | 128 | >128 |
| Epidermophyton floccosum FF9 | 144 | 144 | 16 | 16 |
| Aspergillus niger ATCC 16404 | 288 | 1125 | n.t | n.t |
| Aspergillus fumigatus ATCC 46645 | 576 | 576 | n.t | n.t |
| Aspergillus flavus F44 | 576 | 576 | n.t | n.t |
MIC—minimal inhibitory concentration and MLC—minimal lethal concentration determined by a macrodilution method and expressed as µg/mL; n.t—not tested.