Table 4.
Allergen reagents (molecular components) with the level of specific IgE in Classes 3 and 4 with the positivity in 5 and more patients (according to TURF—total unduplicated reach and frequency). The relation between the level of specific IgE in Classes 3 and 4 and the occurrence of bronchial asthma, allergic rhinitis, the severity of AD, the onset of AD (under 5 years of age or later), family history, and duration of eczematic lesions (persistent or occasional). The levels of significance (p-value) are calculated in the chi-square test (at an expected minimum frequency of at least 5) or in Fisher’s exact test. We show only the significant relation (p-value < 0.05).
| Allergen Reagents, Allergenic Extracts and Molecular Components (Biochemical Name). r = Recombinant, n= Natural | Number of Patients | Severity of AD | Bronchial Asthma | Allergic Rhinitis | Onset of AD | Family History | Duration of Lesion | |
|---|---|---|---|---|---|---|---|---|
| Aca s | Storage mite | 14 | 0.0437 | - | - | - | - | 0.00316 |
| Ach d | House cricket | 15 | - | - | - | - | - | 0.00164 |
| rAln g 1 | PR-10 protein, alder | 31 | - | - | - | - | - | - |
| rAlt a 1 | Unknown, Alternaria alternata | 26 | - | - | - | - | - | - |
| rAlt a 6 | Enolase, Alternaria alternata | 6 | - | 0.0312 | - | - | - | - |
| Amb a | Ragweed | 12 | - | - | - | - | - | - |
| rAmb a 4 | Plant defensin, ragweed | 11 | - | - | - | - | - | - |
| rApi g 1 | PR-10 protein, celery | 14 | - | - | 0.0182 | - | - | - |
| rApi m 10 | Icarapin variant 2, honey bee venom | 6 | - | - | - | - | - | |
| nAra h 1 | Cupin (vicillin-type, 7S globulin), peanut | 5 | 0.0349 | - | - | - | - | - |
| nAra h 6 | 2S albumin, peanut | 5 | 0.0349 | - | - | - | - | - |
| rAra h 8 | PR-10 protein, peanut | 15 | - | - | - | - | - | - |
| Art v | Mugwort | 20 | - | - | - | - | - | - |
| rArt v 1 | Plant defensin, mugwort | 10 | - | - | - | - | - | - |
| rAsp f 6 | Mn superoxide dismutase, Aspergillus fumigatus | 14 | 0.00145 | - | - | 0.00784 | - | 0.0214 |
| rBet v 1 | PR-10 protein, birch | 45 | - | - | 0.009 | - | - | - |
| rBla g 9 | Arginine kinase, German cockroach | 20 | 0.00439 | - | - | - | - | 0.0008 |
| rBlo t 5 | Blomia tropicalis, storage mite | 6 | 0.023 | - | - | - | - | 0.0356 |
| rCan f 1 | Lipocalin, dog | 27 | 0.0235 | - | 0.01 | 0.00262 | - | - |
| rCan f 2 | Lipocalin, dog | 14 | 0.0437 | - | - | 0.00784 | - | - |
| rCan f 4 | Lipocalin, dog | 22 | - | - | - | 0.00623 | - | - |
| rCan f 6 | Lipocalin, dog | 26 | 0.00907 | - | - | - | - | - |
| rCanf_Fel d 1-like | Uteroglobin, dog | 6 | - | - | - | - | - | 0.0356 |
| Can f_male urine | Male dog urine | 20 | - | - | - | - | - | - |
| rCav p 1 | Lipocalin, guinea pig | 16 | - | - | 0.0238 | |||
| rCor a 1.0103 | PR-10 protein, hazel pollen | 39 | 0.0163 | - | 0.0163 | - | - | 0.0482 |
| rCor a 1.0401 | PR-10 protein, hazelnut | 30 | 0.00819 | - | - | - | - | - |
| Cor a_pollen | Hazel pollen | 36 | 0.00728 | - | 0.0164 | - | - | 0.0211 |
| rCra c 6 | Troponin C, North sea shrimp | 5 | 0.0349 | - | - | - | - | - |
| Cyn d | Bermuda grass | 16 | 0.0288 | - | - | - | - | - |
| rCyn d 1 | Beta expansin, Bermuda grass | 24 | 0.00168 | - | 0.0312 | - | - | |
| Dau c | Carrot | 10 | - | - | - | - | - | 0.0402 |
| rDau c 1 | PR-10 protein, carrot | 12 | - | - | 0.0329 | - | - | - |
| rDer f 1 | Cysteine protease, house dust mite | 23 | - | - | 0.0327 | - | - | - |
| rDer f 2 | NPC2 family, house dust mite | 42 | 0.046 | 0.0497 | 0.0384 | |||
| rDer p 1 | Cysteine protease, house dust mite | 25 | - | 0.0485 | - | - | - | - |
| rDer p 2 | NPC2 family, house dust mite | 42 | 0.046 | - | - | 0.0497 | 0.0384 | |
| rDer p 20 | Arginine kinase, house dust mite | 19 | 0.00224 | - | - | - | - | 0.00017 |
| rDer p 21 | Unknown, house dust mite | 14 | 0.0437 | 0.0185 | - | 0.00784 | - | 0.00316 |
| rDer p 23 | Peritrophin-like protein domain, house dust mite | 28 | 0.00785 | 0.0122 | - | - | - | 0.00658 |
| rDer p 5 | Unknown, house dust mite | 15 | - | 0.0482 | - | 0.042 | - | 0.00164 |
| rDer p 7 | Bactericidal permeability-increasing-like protein, house dust mite | 6 | - | 0.0312 | - | - | - | 0.0356 |
| rEqu c 1 | Lipocalin, horse | 19 | - | - | - | - | - | - |
| rFag s 1 | PR-10 protein, European beech | 40 | 0.017 | - | 0.0189 | - | - | 0.032 |
| rFel d 1 | Uteroglobin, cat | 34 | 0.0319 | 0.0291 | 0.00168 | 0.00117 | 0.00476 | |
| rFel d 4 | Lipocalin, cat | 15 | - | - | - | 0.042 | 0.00713 | - |
| rFel d 7 | Lipocalin, cat | 16 | - | - | - | 0.00017 | - | - |
| rFra a 1 + 3 | PR-10 protein+ non-specific lipid transfer protein type 1, strawberry | 26 | - | - | - | - | - | - |
| Fra e | European ash | 10 | - | - | - | - | - | - |
| rFra e 1 | Ole e 1-like protein family, European ash | 11 | - | - | - | - | - | - |
| rGly d 2 | NPC2 family, storage mite | 16 | 0.0455 | - | - | - | - | 0.00085 |
| rGly m 4 | PR-10 protein, soybean | 16 | - | - | - | - | - | - |
| Hom g | Lobster | 6 | 0.0337 | - | - | - | - | - |
| Chi spp. | Crab | 6 | - | - | - | - | - | - |
| rLep d 2 | NPC2 family, storage mite | 28 | 0.0168 | 0.0462 | - | - | - | 0.00154 |
| Loc m | Migratory locust | 10 | - | 0.0402 | - | - | - | 0.0402 |
| nLol p 1 | Beta-espansin, Rye grass | 40 | 0.0132 | 0.0406 | 0.0106 | |||
| Lol spp. | Squid | 5 | - | - | - | - | - | - |
| rMal d 1 | PR-10 protein, apple | 23 | 0.0249 | - | - | - | - | - |
| rMala s 11 | Mn superoxide dismutase, Malassezia sympodialis | 17 | 0.00855 | - | - | - | - | - |
| rMala s 5 | Unknown, Malassezia sympodialis | 6 | - | - | - | - | 0.0103 | - |
| nMus m 1 | Lipocalin and urinary prealbumin, house mouse | 15 | - | - | - | - | 0.00147 | - |
| nOle e 1 | Ole e 1-family, olive | 7 | - | - | - | - | - | 0.0185 |
| rOry c 1 | Lipocalin, rabbit | 5 | - | - | - | - | - | - |
| rOry c 3 | Uteroglobin, rabbit | 24 | 0.0431 | - | - | - | - | 0.041 |
| Pan b | Northern shrimp | 7 | - | - | - | - | - | - |
| Pas n | Bahia grass | 14 | 0.0437 | - | - | - | - | - |
| rPen m 2 | Arginine kinase, shrimp | 12 | 0.0264 | - | - | - | - | 0.001 |
| rPer a 7 | Tropomyosin, American cockroach | 5 | - | - | - | - | - | - |
| rPhl p 1 | Beta expansin, Timothy | 43 | 0.0273 | 0.0298 | - | 0.0482 | - | 0.0251 |
| rPhl p 2 | Expansin, Timothy | 32 | 0.0164 | 0.02 | - | 0.049 | - | 0.0126 |
| rPhl p 5.0101 | Grass group 5/6, Timothy | 37 | - | - | 0.0291 | - | - | 0.04 |
| rPhl p 6 | Grass group 5/6, Timothy | 29 | - | - | 0.0248 | - | - | - |
| rPhod s 1 | Lipocalin, Siberian hamster | 7 | - | - | - | - | - | - |
| Pla l | English plantain | 12 | - | - | - | - | - | - |
| rPla l 1 | Ole e 1-like protein family, English plantain | 12 | - | - | - | - | - | - |
| Rat n | Rat | 8 | - | - | - | - | 0.0267 | - |
| Sec c_pollen | Cultivated rye, pollen | 31 | 0.0118 | 0.00971 | - | - | - | - |
| Ten m | Mealworm | 10 | - | - | - | - | - | 0.0402 |
| Tyr p | Storage mite | 13 | - | 0.0338 | - | - | - | 0.00604 |
| rXip g 1 | Beta-parvalbumin, swordfish | 5 | - | - | - | - | - | - |