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. 2021 May 15;13(5):1687. doi: 10.3390/nu13051687

Table 4.

Characteristics and main findings of longitudinal studies that explored eating frequency.

Longitudinal Studies
Children
Author and Year Population Exposure (s) Outcome (s) Adjusted Variables Results
Franko 2008 [31]. ▪ American (black and white race).
n = 2375 girls.
▪ Age: 9–10 years.
▪ 10 year follow-up.
Meal frequency: number of days consumed ≥ 3 meals (breakfast, snack, lunch or other). BMI-for-age z-score and OW. Visit, study site, parental education, socioeconomic status, race, energy intake and indicators of physical activity. ▪ MF: BMI-for-age z score (β = −0.047, p < 0.01).
Ritchie 2012 [30]. ▪ NGHS study.
▪ American (black and white race).
n = 2372 girls.
▪ Age: 9–10 years.
10 year follow-up.
Eating frequency:
▪ Eating episode: 1–3, 3.1–4, 4.1–6 or >6 per day.
▪ Meal: 1–2.5 or > 2.5 meals per day.
▪ Snack: 0–1, 1.1–2, 2.1–3 or > 3 per day.
BMI and WC. BMI or WC, race, parental education, physical activity,
Television/video viewing, and total energy intake, dieting for weight loss.
▪ >6 total eating episodes/day: <BMI (p = 0.01) and WC (p = 0.04).
▪ >2.5 MF: >BMI (p = 0.04).
Taylor 2017 [4]. ▪ New Zealander.
n = 371 (175 girls and 196 boys).
▪ Age: 1–3.5 years.
▪ 3.5 year follow-up
Eating frequency (all eating occasions). BMI z-score. POI intervention group, household factors, maternal parity/education, infant sex, birth weight, pre-pregnancy BMI, pregnancy smoking, and exclusive breastfeeding. No significant associations.
Adults
Author and Year Population Exposure (s) Outcome (s) Adjusted Variables Results
Kahleova 2017 [67]. ▪ AHS-2.
▪ North American.
n = 50,660.
▪ Age: ≥ 30 years.
▪ 7 ± 1 year follow-up.
Meal frequency and timing:
▪ Breakfast: from 5–11 h.
▪ Lunch: from 12–16 h.
▪ Dinner: from 17–23 h.
BMI. Age, sex, ethnicity, marital status, education, personal income, dietary pattern, exercise, sleep, television watching, energy intake, and high blood pressure medicine. ▪ ≥6 MF vs. 3 MF: BMI (β = 0.04 [95% CI: 0.02, 0.06]).
Larsen 2019 [74]. ▪ MONICA study.
▪ Danish.
n = 2124 (1044 women and 1080 men).
▪ Middle-aged.
▪ 6 year follow-up.
Total eating, meal and snack frequency (self-reported). BMI and WC. Baseline measure of outcome, smoking, alcohol, PA, education, age, gender, menopausal status for women, and height (in WC analysis only). Baseline MF:
▪ 6-y. change: BMI (β = −0.14 [95% CI: −0.27, 0.00]) and WC (β = −0.49 [95% CI: −0.99, 0.00]).

Abbreviations: ADHS-2, Adventist Health Study 2; β, beta coefficient; BMI, body mass index; EF, eating frequency; MF, meal frequency; MONICA, Danish Monitoring Trends and determinants in Cardiovascular Disease; NA, no associations; NGHS, National Heart, Lung, and Blood Institute Growth and Health Study; OR, odds ratio; OW, overweight; PA, physical activity; POI, Prevention of Overweight in Infancy; vs., versus; WC, waist circumference.