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Summary of the main functions of ARHGAP11B and of the NOTCH2NL genes during neocortex development.
| ARHGAP11B | NOTCH2NLA | NOTCH2NLB |
|---|---|---|
| neocortex size ↑ | basal progenitors ↑ | apical progenitor ↑ |
| cortical folding ↑ | basal intermediate progenitors ↑ | cortical progenitor proliferation ↑ |
| cortical plate thickness ↑ | cortical progenitor differentiation ↓ | |
| upper-layer neurons ↑ | neuronal output ↑ | |
| oSVZ thickness ↑ | ||
| basal progenitors ↑ | ||
| basal radial glia ↑ |
