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. 2021 May 17;10(5):788. doi: 10.3390/antiox10050788

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effect of camel milk as an anti-cancer. Camel milk regulates the apoptosis in cancer cells by using extrinsic signaling to mediate ROS production and mRNA expression of DR4. Further, the ROS and DR4 activate the JNK and caspases to regulate the process of apoptosis. Camel milk also inhibits carcinogenesis via intrinsic pathways by down-regulating the cytochrome P450 1A1 (CYP1A1) and up-regulating the NQO1 and glutathione S-transferase a1 (GSTA1), which provide protection against cancer.