Figure 4.

Genomic annotations of the Lag-3 gene locus. The Lag-3 locus is located at chromosome 12: 6,881,678-6,887,621 forward strand. The illustration shows the organization of the Lag-3 locus (http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000089692;r=12:6881678-6887621, accessed on 2 May 2021) [62]. The black bar represents chromosome 12, with positions indicated on top. In green is the Lag-3 coding region. In blue is the transcript retaining one intron. In red is the canonical Lag-3 transcript. In red and blue is the alternatively-spliced Lag-3 transcript. The positions of single-nucleotide polymorphisms are shown below the canonical Lag-3 transcript. The promoter regions are also indicated in pink.