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CD137 stimulation inhibits the outgrowth of C. albicans. (A,B) Mice were intraperitoneally injected with 200 μg of anti-CD137 or control rat IgG antibody 1 day before infection with 3 × 105 CFU of C. albicans. Organs were harvested at 3-d post-infection. (A) Counting of CFUs (n = 5 mice per group). (B) PAS staining of kidney sections. Magnification: 200×. Results are representative of 3 experiments. * p < 0.05; ** p < 0.01 between the two groups.
