Table 1.
List of miRNAs implicated in PCa development.
| miRNA | Expression in PCa | Target | Mechanism | References |
|---|---|---|---|---|
| miR-15/miR16 | downregulated | Cyclin D1,WNT3A | Cell cycle | [67] |
| miR-205 | downregulated | PKCε | Cell cycle | [68,69] |
| PKCε, ZEB1 | EMT | [70] | ||
| miR-34a | downregulated | SIRT1, Wnt, c-Myc, STMN | Apoptosis, cell cycle | [71,72,73,74] |
| miR-21 | overexpressed | KLF5, PTEN | Apoptosis, cell proliferation, invasion and migration | [75,76] |