Table 1.
Clinical and biochemical parameters of the study and the control group (data presented as numbers or mean ± standard deviation and interquartile range).
| Parameter | Study Group | Control Group | p |
|---|---|---|---|
| Number of patients (n) | 50 | 20 | NA |
| Age (years) | 14.76 ± 3.08 (14.42–16.75) |
14.11 ± 2.99 (13.00–16.38) |
0.261 |
| Boys/Girls | 29/21 (58%/42%) |
11/9 (55%/45%) |
0.819 |
| Height (cm) | 166.7 ± 16.51 (160.5–178.5) |
161.9 ± 15.26 (151.5–171.5) |
0.259 |
| Height Z-score | 0.54 ± 0.99 (−0.45–1.16) |
0.69 ± 1.23 (0.13–1.22) |
0.589 |
| Weight (kg) | 70.29 ± 19.6 (61.5–85.0) |
55.2 ± 16.55 (46.0–61.0) |
0.003 |
| Weight Z-score | 1.23 ± 0.80 (0.49–1.83) |
0.61 ± 0.98 (−0.26–1.25) |
0.009 |
| BMI | 24.78 ± 4.63 (21.27–28.89) |
20.67 ± 3.59 (18.30–22.03) |
0.001 |
| BMI Z-score | 1.09 ± 0.82 (0.5–1.78) |
0.35 ± 0.94 (−0.43–1.12) |
0.004 |
| Periostin (ng/mL) | 35.42 ± 10.43 (27.73–39.02) |
42.16 ± 12.82 (32.21–51.45) |
0.038 |
| eGFR acc. to Schwartz (L/min/1.73 m2) | 100.12 ± 21.16 (86.73–115.64) |
108.12 ± 18.48 (95.42–121.9) |
0.100 |
| Uric acid (mg/dL) | 5.56 ± 1.34 (4.7–6.4) |
4.56 ± 1.10 (3.95–5.35) |
0.004 |
| Total cholesterol (mg/dL) | 153.98 ± 33.92 (132.0–168.0) |
154.75 ± 30.71 (135.0–179.5) |
0.927 |
| LDL-cholesterol (mg/dL) | 85.63 ± 30.38 (64.0–95.8) |
81.2 ± 24.19 (63.8–103.6) |
0.654 |
| HDL-cholesterol (mg/dL) | 49.5 ± 10.28 (43.0–53.0) |
61.05 ± 13.05 (52.5–69.5) |
0.001 |
| Triglycerides (mg/dL) | 95.24 ± 43.18 (64.0–120.0) |
64.5 ± 23.86 (49.5–71.5) |
0.002 |
NA: not applicable; BMI: body mass index; eGFR: estimated glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein.