Table 2.
Multivariate logistic regression analysis of parameters predicting amoxicillin/clavulanate resistance in all patients.
| Amoxicillin/Clavulanate Resistance in All Patients with E. coli or K. pneumoniae Urinary Isolate (n = 330; Amoxicillin/Clavulanate Resistance Episodes = 59) | ||
|---|---|---|
| Parameter | Adjusted OR (95% CI) |
p-Value |
| Age | 1.01 (0.99–1.03) | 0.269 |
| Charlson Comorbidity Index | 1.04 (0.93–1.17) | 0.457 |
| SAPS II | 1.02 (0.97–1.06) | 0.496 |
| Immunosuppression | 2.05 (0.85–4.93) | 0.110 |
| Indwelling urinary catheter | 1.84 (0.75–4.51) | 0.183 |
| Prior hospital stay (3 months) | 0.54 (0.21–1.39) | 0.168 |
| Prior fluoroquinolones or amoxicillin/clavulanate use (3 months) | 2.94 (1.55–5.58) | 0.001 |
| CO-HCA UTI | 1.75 (0.78–3.92) | 0.177 |
Multivariate logistic regression model was used for examining independent variables associated with amoxicillin/clavulanate resistance, using stepwise automatic variable selection procedure. All patients of the study (n = 330) were included. Abbreviations: 95% CI: 95% confidence interval, SAPS II: simplified acute physiology score II; CO-HCA UTI: community onset-healthcare associated urinary tract infection.