Table A1.
Supl. Clinical characteristic of the study group.
| Parameter | Study Group n = 59 (100%) |
FA n = 16 (100%) |
ADFA n = 38 (100%) |
AD n = 5 (100%) |
|---|---|---|---|---|
| Clinical symptoms, n (%) | ||||
| skin | ||||
| rush, erythema, xerosis | 46 (77.96) | 3 (18.75) | 38 (100) | 5 (100) |
| itching | 0 | 0 | 17 (44.73) | 2 (40) |
| urticarial/angiooedema | 5 (8.47) | 1 (6.25) | 4 (10.25) | 0 |
| gastrointestinal | ||||
| colic/abdominal pain | 43 (72.88) | 12 (75) | 29 (76.31) | 2 (40) |
| vomiting/massive regurgitation | 26 (44.06) | 6 (37.5) | 19 (50) | 1 (20) |
| weight loss/poor weight gain | 9 (15.25) | 0 | 9 (23.68) | 0 |
| loose of apetite /flatulence/reflection | 6 (10.16) | 2 (12.5) | 4 (10.52) | 0 |
| diarrhea | 24 (40.60) | 8 (50) | 16 (42.10) | 0 |
| blood/mucus in stool | 23 (38.98) | 9 (56.25) | 13 (34.21) | 1 (20) |
| constipation | 2 (3.38) | 1 (6.25) | 0 | 1 (20) |
| others | ||||
| runny nose/snuffles | 9 (15.25) | 5 (31.25) | 4 (10.52) | 0 |
| wheezing | 4 (6.77) | 1 (6.25) | 3 (7.89) | 0 |
| recurrent cough | 2 (3.38) | 1 (6.25) | 1 (2.63) | 0 |
| pallor/cyanosis after ingestion | 6 (10.16) | 3 (18.75) | 3 (7.89) | 0 |
| sweating, weakness after eating food | 3 (5.08) | 2 (12.5) | 1 (2.63) | 0 |
| sIgE, n (%) | ||||
| at least >1 | 10 (16.94) | 2 (12.5) | 8 (21.05) | 0 |
| cow’s milk | 0 | 2 (12.5) | 6 (15.78) | 0 |
| egg | 0 | 0 | 1 (2.63) | 0 |
| wheat | 0 | 0 | 1 (2.63) | 0 |
| peanut | 0 | 0 | 1 (2.63) | 0 |
| SCORAD index, points | ||||
| mean ± SD | 23.77 ± 19 | - | 23.03 ± 17.4 | 29.4 ± 20.8 |
| Atopic dermatitis severity, n (%) | ||||
| Mild <20 pkt | 22 (37.28) | 0 | 20 (52.63) | 2 (40) |
| Moderate 20–40 pkt | 14 (23.72) | 0 | 13 (34.21) | 1 (20) |
| Severe >40 pkt | 7 (11.86) | 0 | 5 (13.15) | 2 (40) |
| AD onset (<12 weeks), n (%) | 35 (59.32) | - | 31 (81.57) | 4 (80) |
| mean ± SD | 6.4 ± 5.4 | - | 6.3 ± 5.3 | 6.6 ± 5.5 |
| Types of CMA from gastrointestinal tract | ||||
| FPIP | 19 (32.20) | 8 (50) | 11 (28.94) | 0 |
| FPIES | 6 (10.16) | 2 (12.5) | 4 (10.52) | 0 |
| FGIDs | 21 (35.59) | 5 (31.25) | 16 (42.10) | 0 |
| IgE-mediated FA | 8 (13.56) | 2 (12.5) | 6 (15.78) | 0 |